Use Caution/Keep an eye on. Ethinyl estradiol could inhibit the clearance of benzodiazepines that undergo oxidation, thus expanding serum concentrations of concomitantly administered benzodiazepines.
Assess Just about every affected person’s threat previous to prescribing and keep an eye on often for the event of those problems
withdrawal reactions, which includes seizures, that may be lifestyle-threatening; use gradual taper when discontinuing therapy to reduce withdrawal reactions risk
eslicarbazepine acetate will reduce the level or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
sage decreases effects of diazepam by pharmacodynamic antagonism. Minor/Importance Unknown. Theoretical interaction; some species of sage may possibly bring about convulsions.
Diazepam is stored preferentially in a few organs, such as the coronary heart. Absorption by any administered route and the potential risk of accumulation is drastically greater from the neonate, and withdrawal of diazepam for the duration of pregnancy and breastfeeding is clinically justified.[113]
It's a presently acknowledged health care use in treatment in America. Abuse could bring about valium sverige confined Actual physical dependence or psychological dependence relative to These in schedule 3.
Monitor Intently (1)enasidenib will boost the amount or influence of diazepam by influencing hepatic enzyme CYP2C19 metabolism.
The prescriber and caregiver needs to have a common idea of what is and is not an episode of seizures which is appropriate for procedure, the timing of administration in relation for the onset in the episode, the mechanics of administering the drug, how and what to observe following administration, and what would represent an end result requiring speedy and direct healthcare notice
topiramate will reduce the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
To view formulary info to start with generate a list of programs. Your record is going to be saved and will be edited at any time.
triclabendazole will enhance the stage or result of diazepam by impacting hepatic enzyme CYP2C19 metabolism.
Keep track of Intently (one)larotrectinib will improve the degree or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Solid or average CYP3A4 inhibitors might lower level of diazepam elimination, thus growing adverse reactions to diazepam.
fluvoxamine will raise the degree or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.